About Us
Our Mission
We develop groundbreaking imaging technology that enables real-time visualization of intracellular oxygen — for the first time. By bringing this capability to the clinic, we aim to transform how oxygen is used as a marker of disease, from improving tumor detection during surgery to enhancing treatment precision in radiotherapy and beyond.
Our Story
Our technology originated from pioneering research in the Optics in Medicine Lab at the Thayer School of Engineering at Dartmouth. What began as a scientific effort to image oxygen at the cellular level has evolved into a mission to bring that innovation to the clinic. Our team brings together expertise in optics, engineering, and oncology, focused on turning this breakthrough into tools that meet real clinical needs and improve patient outcomes.
Our Technology
Our platform uses a unique optical signal emitted by Protoporphyrin IX (PpIX), a molecule that can be induced throughout the body using the FDA-approved prodrug 5-ALA. This signal, known as delayed fluorescence, reveals tissue oxygen levels at the cellular scale. We’ve developed a system that captures this signal across an entire surgical field at video frame rates.
The Team
Brian Pogue, Ph.D.
President
Brian is a Professor of Engineering Sciences, Physics & Astronomy at Dartmouth College, an Adjunct Professor of Surgery at the Geisel School of Medicine, and a Visiting Research Scientist at the Wellman Center for Photomedicine at Massachusetts General Hospital.
Bill Ware
CEO
Bill has held executive leadership roles in companies across various stages, from proof of concept to commercial execution, global growth, and successful exit. With over 20 patented products launched to market, his experience spans industries including pharmaceuticals, oil and gas, textiles, and medical devices.
Petr Bruza, Ph.D.
CTO
Petr is an Assistant Professor at the Thayer School of Engineering at Dartmouth College. His research focuses on quality assurance in radiation oncology and the development of ultra-high dose rate (FLASH) radiotherapy. He brings deep expertise in optical systems, hardware engineering, and biomedical imaging.
Arthur Pétusseau, Ph.D.
CSO
Arthur is an Assistant Professor at the Thayer School of Engineering at Dartmouth College. His research focuses on the development of advanced fluorescence imaging techniques for surgical guidance. Arthur has extensive expertise in imaging system design, manufacturing, and biomedical optics.